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The gradient of the curve y = x2 - 5x + 6 is zero at which of the following values of x ?
x = 2 and x = 3
x = 2.5
x = 6
dy/dx= 2x-5

It has been observed that during prolong animal cell culture and differentiation, cells tends to stop dividing. They are said to be in:
Apoptotic
Quiescent
Senescent
G1

Which of the following is unfavourable for protein folding?
Hydrophobic interaction
vander wall interaction
Conformational entropy
Hydrogen Bonding

Which of the following is most correct?
Charged amino acids are never buried in the interior of a protein.
Charged amino acids are seldom buried in the interior of a protein.
All hydrophobic amino acids are buried when a protein folds
Glycine is rarely found in the interior of proteins because

A bee leaves it hive in the morning and after flying for 30 minutes due south reaches a garden and spend 5 min collecting honey. Then it flies for 40 minutes due west and collect honey in another garden for 10 min. Then it returns to the hive taking the shortest route. How long was the bee away from its hive, it it flies the constant speed?
85 min
155 min
135 min
less than 1 hour

The fact that the core of most globular proteins is tightly packed is due to:
the hydrophobic effect
hydrogen bonding
electrostatic effects
van der Waals forces

Different reversible inhibitors act in different manner and accordingly gives their characteristic Lineweaver-Burk plot. The effect of non-competitive inhibition on a Lineweaver-Burk Plot is that-
it can move the entire curve to the right
it can change the y-intercept
it can change the x-intercept
all of these

For an enzyme substrate reaction following Michaelis Menton kinetics, it is given that an enzyme with a Km = 10m M and Vmax = 100 m mol/min. If [S] = 100 m M, which of the following will be true?
A 10 fold increase in Vmax would increase velocity 10 fold
A 10 fold decrease in Km would increase velocity
Both (a) and (b)
A 10 fold increase in Vmax would decrease velocity 20 fold

Stationary phase is described asA.B.C.D.
no further increase in the cell population after a maximum value
deceleration of growth and division rate after the growth rate reaches a maximum
acceleration of growth and division rate after the growth rate reaches a maximum
deceleration of growth and division rate after the growth rate reaches a minimum

Monod model explain the change in specific growth rate of microrganism growing in a batch fermentor. The monod model predicts that the specific growth rate-
will increase with the concentration of the growth limiting substrate until it reaches a maximum value
will decrease with the concentration of the growth limiting substrate
will increase with the concentration of the growth limiting substrate
does not depend on growth limiting substrate

Airlift bioreactors are used for the fermentation of shear senstive cells. The high oxygen transfer efficiencies of airlift bioreactors is due to?
the large aspect ratio of the reactor, which leads to a high gas hold-up
the large aspect ratio of the reactor, which leads to a high oxygen solubility at the base of the reactor
the draft tube, which reduces bubble coalescence in the reactor
all of the above

For bacterial cells growing in batch culture, doubling time given is calculated during exponential phase. Population doubling time, td can be expressed as (where µ is the specific growth rate.
log2/µ
ln2/µ
µ/ln2
µ/log2

The increased air flow rate in bubble column fermenter can cause excessive foaming and high retention of air bubbles in the column which?
decreases the productivity of the fermenter
increases the productivity of the fermenter
modestly increases the productivity of the fermenter
does not affect on the productivity

Which of the following is considered as a disadvantage to the adsorption method of immobilization?A.B.C.D.
It is possible to separate and purify the enzymes while being immobilized
The enzymes are not usually deactivated by adsorption
The adsorption is a reversible process
State of immobilization is very sensitive to solution pH, ionic strength and temperature

The average concentration of oxygen in the boundary layers surrounding the bubbles (Co*) in a reactor is normally determined by-
ultra-small dissolved oxygen probes
laser based photographic systems
measuring the steady state concentration of oxygen in the bulk liquid prior to inoculation of the reactor
measuring the steady state concentration of oxygen in the bulk liquid after inoculation of the reactor

Why vortexing is undesirable in the agitation of biological systems?A.B.C.D.
The collision between the cells, impeller and air bubbles will lead to cell damage
Poor mixing despite the use of high stirrer speeds
Mixing will not be in the turbulent region
All of the above

If A= (elements in the matrix belong to complex number i)then |A| = ?
2
3
4
5

The number of non-zero rows in an echlon form is called ?
reduced echlon form
rank of a matrix
conjugate of the matrix
cofactor of the matrix

-1/2
-1/32
1/8
2

If f( x) = Sin6x + Cos6x, then
f(x)< or equal to 1
f(x)< or equal to 2
f(x) >1/4
f(x) >1/8

Under alkaline conditions, DNA is more stable than RNA because-
RNA forms secondary structures
RNA is a single stranded molecule
RNA has uracil in place of thymidine
RNA is susceptible to hydrolysis

Adjuvants are often mixed to the vaccines before vaccination. The role of an adjuvant is to
prolong the persistence of antigen
cross link the antigen
increase the size of antigen
avoid inflammation

Which one of the following is an ABC transporter?
acetylcholine receptor
ATP synthase
multidrug resistance protein
bacteriorhodopsin

Two proteins that share 40% amino acid identity are-
40 % homologous
60 % not homologous
May be homologous
Can not be homologus

In nature, Agrobacterium tumefaciens mediated infection of plant cells leads toP. crown gall disease in plantsQ. hairy root disease in plantsR. transfer of T-DNA into the plant chromosomeS. transfer of Ri-plasmid into the plant cell
S only
P and R only
Q ans S only
Q only

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Aarohan Biotek

Tests Created: 1

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Discussion

Kaustubh

bakwas, i start 5 or more time , nothing happened.

2131 days 7 hours 16 minutes ago

Keerthana.K

Hi,where i can get the answers?

2188 days 23 hours 10 minutes ago

V Parimala Rao

where can i get the answer key for this

2402 days 4 hours 16 minutes ago

Aarohan Biotek

Congratulations to Vishakha for getting highest score in the last online test for GATE BT 2015.

2762 days 22 hours 44 minutes ago

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