Analytical Research & Development

Acetic acid content by GC for Irbesartan (Method 2 ) Medium : DMSO Method of analysis: Column: HP-INNOWAX 30mts x 0.53mm, 1µm Detector temp : 230°C Injector temp: 100°C Injection mode : Split Split ratio: 10:1 Linear velocity : 55cm/sec Temperature Programme: Initial temp : 60°C Initial time : 1 min Rate 1 : 20°C/min Holding temp : 150°C Holding time : 4 min Rate 2 : 40°C/min Final temp: 210°C Final time : 4 min Chromatogram attached. Acetic acid RT = ~ 6.0 minutes. Total run time = ~ 15 minutes.