Cell Cycle

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Slide 1 : APT ACADEMIC SOLUTIONS

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Slide 4 : Session Objectives Cell cycle To Study the types of cell division Mitosis Meiosis Amitosis Endomitosis c-Mitosis Significances of different types of cell reproduction

Cell Cycle : Cell Cycle Interphase

Cell Cycle : Cell Cycle Phases of Cell Cycle are G1 S G2 M

Phases of Cell Cycle : Phases of Cell Cycle G1 Phase Proteins are synthesized Proteins are enzymatic in nature S Phase DNA are synthesized Histone proteins are synthesized

Slide 8 : Phases of Cell Cycle G2 Phase Proteins are synthesized Proteins are structural in nature Tubulin proteins are synthesized Genetic material can be represented as 4C M Phase Divided into Karyokinesis & Cytokinesis What is G0 phase ?

Mitosis : Mitosis Mitosis Cytokinesis

Interphase : Interphase Metabolically the most active Stage Indistinct chromosome Intact nuclear membrane Centriole divides

Prophase (Early) : Prophase (Early) Condensation of Chromosome Chromosome splits into Chromatids Nuclear membrane & nucleolus remain intact

Prophase (Late) : Prophase (Late) Chromatids are randomly distributed in cell Nuclear membrane & nucleolus disappear Spindle fibres are formed & attached to centromere

Metaphase : Metaphase Chromosome are fully condensed Chromatids are arranged at the equatorial plate called metaphase plate Best stage for the study of chromosome

Anaphase : Anaphase Centromere divides Spindle fiber contracts Chromatids become V-shape Chromatid moves to their respective poles

Telophase : Telophase Reverse to Prophase Condensation of chromosome occurs Chromosome become thicker & thinner Spindle fibre disorganize Nuclear membrane & nucleolus reapperars

Cytokinesis : Cytokinesis Plants ER, Golgi bodies & IZ fibre form Fragmoplast Fragmoplast forms cell plate Cell plate formation is centripetal

Cytokinesis : Cytokinesis Animal ER, Golgi bodies & IZ fibre form midbody Midbody helps in the formation of cell furrow Centrifugal pattern

Illustrative Problem : Illustrative Problem Mitosis can be best studied in ? Root tips Shoot tips Leaf tips Floral tis Root tips lacks natural pigments, hence, chromosome can be easily stained

Illustrative Problem : Illustrative Problem What is the number of mitotic division required to form 100 cells ? 25 50 99 100 No. of Mitotic Div. = n – 1 Where n = no. of cells

Meiosis : Meiosis Meiosis was first noticed by Strasburger in 1888, although the term meiosis was coined in 1905 by J.B. Farmer and J.E. Morre Occurs in germ cells Immature anther is the best material to study the division Four daughter cells are formed Chromosome number is reduced by half

Meiosis : Meiosis Interphase Cytokinesis

Meiosis I : Meiosis I Chormosome appear As thin thread like structure Bouquet Arrangement are observed Nuclear membrane & nucleolus remains intact

Meiosis I : Meiosis I Condensation of chromosome occurs Homologous chromosomes get paired The pairing is known as synapsis or syndesis Pairing occurs with the help of synaptonemal complex

Meiosis I : Meiosis I Condesation results into spliting of chromosome into chromatids & tetrads are formed Exchange of genetic materials takes place between non-sister chromatids & the process is known as crossing over The regions where crossing over takes place are called chiasmata (singular chiasma)

Meiosis I : Meiosis I Homologous chromosomes repel each other Terminalization of the chiasma begins Synaptonemal complex disorganizes

Meiosis I : Meiosis I Nuclear membrane & nucleolus disappear Spindle fibres are formed Chiasma fully terminalized

Meiosis I : Meiosis I Metaphase I Chromosome organize themselves at the equatorial plate

Meiosis I : Meiosis I Anaphase I Disjunction of the chromosome Contraction of the spindle fibre resulting into movement of the chromosome at their respective poles Actual reduction in the chromosome no.

Meiosis I : Meiosis I Telophase I

Meiosis : Meiosis Intrameiotic Interphase (Interkinesis) Stage between telophase of first meiotic division and prophase of second meiotic division No replication of DNA Similar to Interphase except the S- Phase

Meiosis II : Meiosis II Prophase II

Meiosis II : Meiosis II Metaphase II

Meiosis II : Meiosis II Anaphase II

Meiosis II : Meiosis II Telophase II and Cytokinesis

Slide 35 : Centromere on the metaphase plate Arms are directed towards the pole Centromere directed towards the pole Arms are on metaphase plate

Slide 36 : Centromere divides Disjunction of the chromosome Metaphase Anaphase

Significance of meiosis : Significance of meiosis Crossing over in meiosis enables genetic variation in organisms Compensates for the doubling of chromosomes at gametic fusion and thus helps to keep the number of chromosomes constant Variations coupled with heredity leads to organic evolution

Illustrative Problem : Illustrative Problem What is the number of meiotic division required to form 100 male gamete ? 25 50 99 100 No. of meiotic div. = n / 4 Where n = no. of male gamete

Illustrative Problem : Illustrative Problem What is the number of meiotic division required to form 102 male gamete ? 25 26 27 25.5 Gametes can be formed only after completion of the division

Illustrative Problem : Illustrative Problem What is the number of meiotic division required to form 100 female gamete or egg cell ? 25 50 99 100 During the formation of the female gamete, 3 cells degenerate and only one survive to develop into egg cell Hence, No. of meiotic div. for egg cell = n, where n = no. of egg cell

Illustrative Problem : Illustrative Problem What is the number of meiotic division required to form 100 seeds ? 25 50 100 125

Illustrative Problem : Illustrative Problem What is the number of meiotic division required to form 103 seeds ? 128 128.5 128.75 129

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