Slide 1 : 6/29/2010 Lecture 8: BIOMEDICINE 1 Online Bioscience Course for IT Professionals
Spring 2010
Slide 2 : 6/29/2010 Lecture 8: BIOMEDICINE 2 Class mechanics… View online video lecture every Monday (1-2 hour)
Comment on video lecture using website discussion
board
Attend the online Office Hour on Wednesday at 12 NOON
online using WizIQ.com and webcam
Online Final Exam given 7/14/2010*
* There are 2 more video lectures, which pushes the last date
of class to 7/12/2010 and the date for the Final Exam to
7/14/2010
Slide 3 : 6/29/2010 Lecture 8: BIOMEDICINE 3 Lecture 8: Biomedicine
Slide 4 : 6/29/2010 Lecture 8: BIOMEDICINE 4 Biomedical research: http://www.youtube.com/watch?v=190lGflP1Fs
Slide 5 : 6/29/2010 Lecture 8: BIOMEDICINE 5 Take Homes: Microbes and disease
II. Genes and disease
III. Medical imaging
IV. Pharmaceuticals/Biotechnology
V. Electronic Medical Records
Slide 6 : 6/29/2010 Lecture 8: BIOMEDICINE 6 Germ theory of disease: The germ theory of disease, also called the pathogenic theory of medicine, is a theory that proposes that microorganisms are the cause of many diseases. Although highly controversial when first proposed, it is now a cornerstone of modern medicine and clinical microbiology, leading to such important innovations as antibiotics and hygienic practices http://en.wikipedia.org/wiki/Germ_theory
Slide 7 : 6/29/2010 Lecture 8: BIOMEDICINE 7 How bacteria cause disease: http://www.youtube.com/watch?v=0Sx51LC_wcc
Slide 8 : 6/29/2010 Lecture 8: BIOMEDICINE 8 Antibiotics: In common usage, an antibiotic (from the Ancient Greek: ??t? – anti, "against", and ß??? – bios, "life") is a substance or compound that kills, or inhibits the growth of, bacteria. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused by microorganisms, including fungi and protozoa.
Note that antibiotics do not affect viruses… http://en.wikipedia.org/wiki/Antibiotic
Slide 9 : 6/29/2010 Lecture 8: BIOMEDICINE 9 Flu attack! How a virus invades
your body: http://www.youtube.com/watch?v=Rpj0emEGShQ
Slide 10 : 6/29/2010 Lecture 8: BIOMEDICINE 10 Vaccination: http://www.youtube.com/watch?v=3ykHoIKAtQI
Slide 11 : 6/29/2010 Lecture 8: BIOMEDICINE 11 MedlinePlus: MedlinePlus is a free Web site that provides consumer health information for patients, families, and health care providers. MedlinePlus brings together quality information from the United States National Library of Medicine, the National Institutes of Health (NIH), other U.S. government agencies, and health-related organizations. The U.S. National Library of Medicine produces and maintains MedlinePlus. http://en.wikipedia.org/wiki/MedlinePlus
Slide 12 : 6/29/2010 Lecture 8: BIOMEDICINE 12 Take Home I Bacteria and viruses are the causative agents of disease and can be treated by a variety of means, including antibiotics and vaccines… Microbes and disease
Slide 13 : 6/29/2010 Lecture 8: BIOMEDICINE 13 Genes and disease: The Mendelian Inheritance in Man project is a database that catalogues all the known diseases with a genetic component, and—when possible—links them to the relevant genes in the human genome and provides references for further research and tools for genomic analysis of a catalogued gene. http://en.wikipedia.org/wiki/Mendelian_Inheritance_in_Man
Slide 14 : 6/29/2010 Lecture 8: BIOMEDICINE 14 What are SNPs?: http://www.youtube.com/watch?v=5raJePXu0OQ
Slide 15 : 6/29/2010 Lecture 8: BIOMEDICINE 15 23andMe: https://www.23andme.com
Slide 16 : 6/29/2010 Lecture 8: BIOMEDICINE 16 What is Cancer: http://www.youtube.com/watch?v=LEpTTolebqo
Slide 17 : 6/29/2010 Lecture 8: BIOMEDICINE 17 Oncogenes I: An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a tumor cell. http://en.wikipedia.org/wiki/Oncogene
Slide 18 : 6/29/2010 Lecture 8: BIOMEDICINE 18 Oncogenes II: http://www.youtube.com/watch?v=WZdErhuLCtc
Slide 19 : 6/29/2010 Lecture 8: BIOMEDICINE 19 How a Proto Oncogene Becomes
an Oncogene: http://www.youtube.com/watch?v=2wIVwZksIt4
Slide 20 : 6/29/2010 Lecture 8: BIOMEDICINE 20 Tumor Suppressors: http://www.youtube.com/watch?v=iLK3jy-kGvs
Slide 21 : 6/29/2010 Lecture 8: BIOMEDICINE 21 Metastasis: http://www.youtube.com/watch?v=rrMq8uA_6iA
Slide 22 : 6/29/2010 Lecture 8: BIOMEDICINE 22 Take Home II Some diseases, such as cancer, have as their root causes mutations and variations in genes… Genes and disease
Slide 23 : 6/29/2010 Lecture 8: BIOMEDICINE 23 Medical imaging : Medical imaging is the technique and process used to create images of the human body (or parts and function thereof) for clinical purposes (medical procedures seeking to reveal, diagnose or examine disease) or medical science (including the study of normal anatomy and physiology).
As a discipline and in its widest sense, it is part of biological imaging and incorporates radiology (in the wider sense), nuclear medicine, investigative radiological sciences, endoscopy, (medical) thermography, medical photography and microscopy (e.g. for human pathological investigations).
Measurement and recording techniques which are not primarily designed to produce images, such as electroencephalography (EEG), magnetoencephalography (MEG), Electrocardiography (EKG) and others, but which produce data susceptible to be represented as maps (i.e. containing positional information), can be seen as forms of medical imaging. http://en.wikipedia.org/wiki/Medical_imaging
Slide 24 : 6/29/2010 Lecture 8: BIOMEDICINE 24 Medical Imaging presentation
Slide 25 : 6/29/2010 Lecture 8: BIOMEDICINE 25 More Than Science Fiction: http://www.youtube.com/watch?v=wjWHx2qOyOY
Slide 26 : 6/29/2010 Lecture 8: BIOMEDICINE 26 Take Home III Medical imaging technologies allow the visualization of medical states of the body and have become a key part of biomedicine… Medical imaging
Slide 27 : 6/29/2010 Lecture 8: BIOMEDICINE 27 Pharmaceuticals/Biotechnology: A pharmaceutical drug, also referred to as medicine, medication or medicament, can be loosely defined as any chemical substance intended for use in the medical diagnosis, cure, treatment, or prevention of disease… http://en.wikipedia.org/wiki/Pharmaceutical_drug Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use… http://en.wikipedia.org/wiki/Biotechnology
Slide 28 : 6/29/2010 Lecture 8: BIOMEDICINE 28 The Biotechnology Age: http://www.youtube.com/watch?v=He91k5wFYcM
Slide 29 : 6/29/2010 Lecture 8: BIOMEDICINE 29 Take Home IV Pharmaceutical and biotechnology based drugs and treatments are the cornerstone of modern biomedicine… Pharmaceuticals/Biotechnology
Slide 30 : 6/29/2010 Lecture 8: BIOMEDICINE 30 Electronic medical records: An electronic medical record is usually a computerized legal medical record created in an organization that delivers care, such as a hospital and doctor's surgery http://en.wikipedia.org/wiki/Electronic_medical_record
Slide 31 : 6/29/2010 Lecture 8: BIOMEDICINE 31 IBM Smarter Planet: Electronic
Health Records for Evolving
Healthcare: http://www.youtube.com/watch?v=OeaksbGMp8Y
Slide 32 : 6/29/2010 Lecture 8: BIOMEDICINE 32 Medical records-back to the future: 1961 electronic medical records http://www.youtube.com/watch?v=t-aiKlIc6uk
Slide 33 : 6/29/2010 Lecture 8: BIOMEDICINE 33 Take Home V Electronic Medical Records (EMRs) are an emerging application of information technology in the field of biomedicine… Electronic Medical Records
Slide 34 : 6/29/2010 Lecture 8: BIOMEDICINE 34 Next Week:
The ecosystem An overview of the Earth’s biological systems…
Slide 35 : 6/29/2010 Lecture 8: BIOMEDICINE 35 instructor
Mark E Minie PhD
mark@meminie.com