CELL STRUCTURE AND FUNCTION : 6&7(CH4) 1 CELL STRUCTURE AND FUNCTION CHAPTER- 4
LECTURE NUMBER:6 & 7
OUTLINE: CELL STRUCTURE AND FUNCTION : 6&7(CH4) 2 OUTLINE: CELL STRUCTURE AND FUNCTION The Cell Theory
Cell Membranes
Getting through Membranes
Cell Size
Organelles composed of Membranes
Nonmembranous Organelles
Nuclear Components
Major Cell Types
Lecture Numbers: Six & Seven : 6&7(CH4) 3 Lecture Numbers: Six & Seven Organelles composed of Membranes
Nonmembranous Organelles
Nuclear Components
Major Cell Types
Organelles composed of membranes : 6&7(CH4) 4 Organelles composed of membranes Plasma membrane (cell membrane)
Endoplasmic reticulum
Golgi apparatus
Lysosomes
Peroxisomes
Vacuoles and vesicles
Nuclear membrane
The plasma membrane : 6&7(CH4) 5 The plasma membrane Composed of a single phospholipid bilayer
Separates the contents of the cell from the external environment
Important features
Metabolic activities
Moving molecules across the membrane
Structurally different inside and outside
Identification: Self vs. nonself
Attachment sites
Signal transduction
CELL ORGANELLES : 6&7(CH4) 6 CELL ORGANELLES Cells are complex structures and have many subunits called organelles.
Each one of the organelles has its function, shape, and structure.
The endoplasmic reticulum : 6&7(CH4) 7 The endoplasmic reticulum A set of folded membranes and tubes throughout the cell.
Provides a large surface area for important chemical reactions.
Because it is folded, it fits into a small space.
Two types of ER
Rough
Has ribosomes on its surface
Sites of protein synthesis
Smooth
Lacks ribosomes
Metabolizes fats
Detoxifies damaging chemicals
The Golgi apparatus : 6&7(CH4) 8 The Golgi apparatus Stacks of flattened membrane sacs.
Functions
Modifies molecules that were made in other places.
Manufactures some polysaccharides and lipids.
Packages and ships molecules.
Traffic through the Golgi : 6&7(CH4) 9 Traffic through the Golgi Vesicles bring molecules from the ER that contain proteins.
Vesicles fuse with the Golgi apparatus.
The Golgi finishes the molecules and ships them out in other vesicles.
Some are transported to other membrane structures.
Some are transported to the plasma membrane.
Some vesicles become lysosomes.
Lysosomes : 6&7(CH4) 10 Lysosomes Vesicles containing enzymes that digest macromolecules.
Carbohydrates
Proteins
Lipids
Nucleic acids
Interior contains low pH
These enzymes only work at pH=5.
The cytoplasm is pH=7.
If the lysosome breaks open, these enzymes will inactivate and will not damage the cell.
Functions of lysosomes : 6&7(CH4) 11 Functions of lysosomes Digestion
of food taken into the cell
Destruction
Disease-causing organisms
Old organelles
Peroxisomes : 6&7(CH4) 12 Peroxisomes Contain the enzyme catalase
Breaks down hydrogen peroxide
Breaks down long-chain fatty acids
Synthesizes cholesterol and bile salts
Synthesizes some lipids
Vacuoles and vesicles : 6&7(CH4) 13 Vacuoles and vesicles Membrane-enclosed sacs
Vacuoles
Larger sacs
Contractile vacuoles
Forcefully expel excess water from the cytoplasm
Vesicles
Smaller vesicles
The nuclear membrane : 6&7(CH4) 14 The nuclear membrane Separates the genetic material from the rest of the cell
Filled with nucleoplasm
Composed of two bilayers
Contains holes called nuclear pore complexes
Allow large molecules like RNA to pass through the membrane into the cytoplasm
Interconversion of membranes : 6&7(CH4) 15 Interconversion of membranes Membranes are converted from one membranous organelle to another.
Energy converting organelles : 6&7(CH4) 16 Energy converting organelles Mitochondrion
A small bag with a large bag stuffed inside.
Larger internal bag is folded into cristae.
Cristae contain proteins for cellular respiration.
Releases the energy from food
Requires oxygen
Uses the energy to make ATP
Energy converting organelles : 6&7(CH4) 17 Energy converting organelles Chloroplasts
Sac-like organelle
Contain chlorophyll
Perform photosynthesis
Uses the energy in light to make sugar
Contain folded membranes called thylakoids
Thylakoids stacked into grana
Thylakoids contain chlorophyll and other photosynthetic proteins.
Thylakoids surrounded by stroma
Nonmembranous organelles : 6&7(CH4) 18 Nonmembranous organelles Ribosomes
Cytoskeleton
Centrioles
Cilia flagella
Inclusions
Ribosomes : 6&7(CH4) 19 Ribosomes Made of RNA and proteins
Composed of two subunits
Large
Small
Are the sites of protein production
Found in two places
Free floating in the cytoplasm
Attached to endoplasmic reticulum
Cytoskeleton : 6&7(CH4) 20 Cytoskeleton Provides shape, support and movement
Made up of
Microtubules
Microfilaments
Intermediate filaments
CELL ORGANELLES : 6&7(CH4) 21 CELL ORGANELLES
CELL ORGANELLES : 6&7(CH4) 22 CELL ORGANELLES
Centrioles : 6&7(CH4) 23 Centrioles Two sets of microtubules arranged at right angles to each other.
Located in a region called the centrosome.
Microtubule-organizing center near nucleus.
Organize microtubules into spindles used in cell division.
Cilia and Flagella : 6&7(CH4) 24 Cilia and Flagella Hair-like projections extending from the cell.
Flagella
Long and few in number
Move the cell through its environment
Cilia
Small and numerous
Move the environment past the cell
9 + 2 arrangement of microtubules
CELL ORGANELLES : 6&7(CH4) 25 CELL ORGANELLES
Inclusions : 6&7(CH4) 26 Inclusions Collections of miscellaneous materials
Can be called granules
Temporary sites for the storage of nutrients and waste
Nuclear components : 6&7(CH4) 27 Nuclear components Contains chromatin
DNA + proteins
Becomes condensed during cell division into chromosomes.
Surrounded by nuclear membrane
Contains one or more nucleoli
Site of ribosome synthesis
Contains nucleoplasm
Water, nucleic acids, etc.
Prokaryotic cells : 6&7(CH4) 28 Prokaryotic cells Two different types of prokaryotes
Domain eubacteria
Contains bacteria
Domain archaea
Contains prokaryotes that live in extreme environments
Prokaryotic cell structure : 6&7(CH4) 29 Prokaryotic cell structure Contain DNA and enzymes
Able to reproduce
Engage in metabolism
Surrounded by a plasma membrane
Plasma membrane surrounded by a cell wall
Maintains the shape of the cell
Cell wall surrounded by a capsule
Helps them adhere to hosts
Protects them from destruction
Contain ribosomes
May contain flagella
Facilitates movement
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Summary of cell organelles and their functions : 6&7(CH4) 32 Summary of cell organelles and their functions