Slide 1 : Essentials of Human Anatomy & Physiology Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Seventh Edition Elaine N. Marieb Chapter 14The Digestive System and Body Metabolism
Slide 2 : The Digestive System and Body Metabolism Slide 14.1 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Digestion
Breakdown of ingested food
Absorption
Passage of nutrients into the blood
Metabolism
Production of cellular energy (ATP)
Slide 3 : Organs of the Digestive System Slide 14.2a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Two main groups
Alimentary canal – continuous coiled hollow tube
Accessory digestive organs
Slide 4 : Organs of the Digestive System Slide 14.2b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.1
Slide 5 : Organs of the Alimentary Canal Slide 14.3 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Mouth
Pharynx
Esophagus
Stomach
Small intestine
Large intestine
Anus
Slide 6 : Mouth (Oral Cavity) Anatomy Slide 14.4 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Lips (labia) – protect the anterior opening
Cheeks – form the lateral walls
Hard palate – forms the anterior roof
Soft palate – forms the posterior roof
Uvula – fleshy projection of the soft palate Figure 14.2a
Slide 7 : Mouth (Oral Cavity) Anatomy Slide 14.5 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Vestibule – space between lips externally and teeth and gums internally
Oral cavity – area contained by the teeth
Tongue – attached at hyoid and styloid processes of the skull, and by the lingual frenulum Figure 14.2a
Slide 8 : Mouth (Oral Cavity) Anatomy Slide 14.6 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Tonsils
Palatine tonsils
Lingual tonsil Figure 14.2a
Slide 9 : Processes of the Mouth Slide 14.7 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Mastication (chewing) of food
Mixing masticated food with saliva
Initiation of swallowing by the tongue
Allowing for the sense of taste
Slide 10 : Pharynx Anatomy Slide 14.8 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Nasopharynx – not part of the digestive system
Oropharynx – posterior to oral cavity
Laryngopharynx – below the oropharynx and connected to the esophagus Figure 14.2a
Slide 11 : Pharynx Function Slide 14.9 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Serves as a passageway for air and food
Food is propelled to the esophagus by two muscle layers
Longitudinal inner layer
Circular outer layer
Food movement is by alternating contractions of the muscle layers (peristalsis)
Slide 12 : Esophagus Slide 14.10 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Runs from pharynx to stomach through the diaphragm
Conducts food by peristalsis (slow rhythmic squeezing)
Passageway for food only (respiratory system branches off after the pharynx)
Slide 13 : Layers of Alimentary Canal Organs Slide 14.11a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Mucosa
Innermost layer
Moist membrane
Surface epithelium
Small amount of connective tissue (lamina propria)
Small smooth muscle layer
Slide 14 : Layers of Alimentary Canal Organs Slide 14.11b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Submucosa
Just beneath the mucosa
Soft connective tissue with blood vessels, nerve endings, and lymphatics
Slide 15 : Layers of Alimentary Canal Organs Slide 14.12 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Muscularis externa – smooth muscle
Inner circular layer
Outer longitudinal layer
Serosa
Outermost layer – visceral peritoneum
Layer of serous fluid-producing cells
Slide 16 : Layers of Alimentary Canal Organs Slide 14.13 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.3
Slide 17 : Stomach Anatomy Slide 14.15a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Located on the left side of the abdominal cavity
Food enters at the cardioesophageal sphincter
Slide 18 : Stomach Anatomy Slide 14.15b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Regions of the stomach
Cardiac region – near the heart
Fundus
Body
Phylorus – funnel-shaped terminal end
Food empties into the small intestine at the pyloric sphincter
Slide 19 : Stomach Anatomy Slide 14.16a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Rugae – internal folds of the mucosa
External regions
Lesser curvature
Greater curvature
Slide 20 : Stomach Anatomy Slide 14.16b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Layers of peritoneum attached to the stomach
Lesser omentum – attaches the liver to the lesser curvature
Greater omentum – attaches the greater curvature to the posterior body wall
Contains fat to insulate, cushion, and protect abdominal organs
Slide 21 : Stomach Anatomy Slide 14.17 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.4a
Slide 22 : Stomach Functions Slide 14.18 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Acts as a storage tank for food
Site of food breakdown
Chemical breakdown of protein begins
Delivers chyme (processed food) to the small intestine
Slide 23 : Specialized Mucosa of the Stomach Slide 14.19 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Simple columnar epithelium
Mucous neck cells – produce a sticky alkaline mucus
Gastric glands – secrete gastric juice
Chief cells – produce protein-digesting enzymes (pepsinogens)
Parietal cells – produce hydrochloric acid
Endocrine cells – produce gastrin
Slide 24 : Structure of the Stomach Mucosa Slide 14.20a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Gastric pits formed by folded mucosa
Glands and specialized cells are in the gastric gland region
Slide 25 : Structure of the Stomach Mucosa Slide 14.20b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.4b, c
Slide 26 : Small Intestine Slide 14.21 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings The body’s major digestive organ
Site of nutrient absorption into the blood
Muscular tube extending form the pyloric sphincter to the ileocecal valve
Suspended from the posterior abdominal wall by the mesentery
Slide 27 : Subdivisions of the Small Intestine
“Dogs Just Itch! Slide 14.22 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Duodenum
Attached to the stomach
Curves around the head of the pancreas
Jejunum
Attaches anteriorly to the duodenum
Ileum
Extends from jejunum to large intestine
Slide 28 : Chemical Digestion in the Small Intestine Slide 14.23a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Source of enzymes that are mixed with chyme
Intestinal cells
Pancreas
Bile enters from the gall bladder
Slide 29 : Chemical Digestion in the Small Intestine Slide 14.23b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.6
Slide 30 : Villi of the Small Intestine Slide 14.24 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Fingerlike structures formed by the mucosa
Give the small intestine more surface area Figure 14.7a
Slide 31 : Microvilli of the Small Intestine Slide 14.25 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Small projections of the plasma membrane
Found on absorptive cells Figure 14.7c
Slide 32 : Structures Involved in Absorption of Nutrients Slide 14.26 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Absorptive cells
Blood capillaries
Lacteals (specialized lymphatic capillaries) Figure 14.7b
Slide 33 : Folds of the Small Intestine Slide 14.27 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Called circular folds or plicae circulares
Deep folds of the mucosa and submucosa
Do not disappear when filled with food
The submucosa has Peyer’s patches (collections of lymphatic tissue)
Slide 34 : Digestion in the Small Intestine Slide 14.57a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Enzymes from the brush border
Break double sugars into simple sugars
Complete some protein digestion
Pancreatic enzymes play the major digestive function
Help complete digestion of starch (pancreatic amylase)
Carry out about half of all protein digestion (trypsin, etc.)
Slide 35 : Digestion in the Small Intestine Slide 14.57b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Pancreatic enzymes play the major digestive function (continued)
Responsible for fat digestion (lipase)
Digest nucleic acids (nucleases)
Alkaline content neutralizes acidic chyme
Slide 36 : Absorption in the Small Intestine Slide 14.59 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Water is absorbed along the length of the small intestine
End products of digestion
Most substances are absorbed by active transport through cell membranes
Lipids are absorbed by diffusion
Substances are transported to the liver by the hepatic portal vein or lymph
Slide 37 : Propulsion in the Small Intestine Slide 14.60 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Peristalsis is the major means of moving food
Segmental movements
Mix chyme with digestive juices
Aid in propelling food
Slide 38 : Large Intestine Slide 14.28 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Larger in diameter, but shorter than the small intestine
Frames the internal abdomen
Slide 39 : Large Intestine Slide 14.28 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.8
Slide 40 : Functions of the Large Intestine Slide 14.29 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Absorption of water
Eliminates indigestible food from the body as feces
Does not participate in digestion of food
Goblet cells produce mucus to act as a lubricant
Slide 41 : Structures of the Large Intestine Slide 14.30a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Cecum – saclike first part of the large intestine
Appendix
Accumulation of lymphatic tissue that sometimes becomes inflamed (appendicitis)
Hangs from the cecum
Slide 42 : Structures of the Large Intestine Slide 14.30b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Colon
Ascending
Transverse
Descending
S-shaped sigmoidal
Rectum
Anus – external body opening
Slide 43 : Structures of the Large Intestine Slide 14.30b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Colon
Ascending
Transverse
Descending
S-shaped sigmoidal
Rectum
Anus – external body opening
Slide 44 : Food Breakdown and Absorption in the Large Intestine Slide 14.61 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings No digestive enzymes are produced
Resident bacteria digest remaining nutrients
Produce some vitamin K and B
Release gases
Water and vitamins K and B are absorbed
Remaining materials are eliminated via feces
Slide 45 : Propulsion in the Large Intestine Slide 14.62 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Sluggish peristalsis
Mass movements
Slow, powerful movements
Occur three to four times per day
Presence of feces in the rectum causes a defecation reflex
Internal anal sphincter is relaxed
Defecation occurs with relaxation of the voluntary (external) anal sphincter
Slide 46 : Accessory Digestive Organs Slide 14.32 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Salivary glands
Teeth
Pancreas
Liver
Gall bladder
Slide 47 : Salivary Glands Slide 14.33 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Saliva-producing glands
Parotid glands – located anterior to ears
Submandibular glands
Sublingual glands
Slide 48 : Saliva Slide 14.34 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Mixture of mucus and serous fluids
Helps to form a food bolus
Contains salivary amylase to begin starch digestion
Dissolves chemicals so they can be tasted
Slide 49 : Teeth Slide 14.35a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings The role is to masticate (chew) food
Humans have two sets of teeth
Deciduous (baby or milk) teeth
20 teeth are fully formed by age two
Slide 50 : Teeth Slide 14.35b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Permanent teeth
Replace deciduous teeth beginning between the ages of 6 to 12
A full set is 32 teeth, but some people do not have wisdom teeth
Slide 51 : Classification of Teeth Slide 14.36a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Incisors
Canines
Premolars
Molars
Slide 52 : Classification of Teeth Slide 14.36b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.9
Slide 53 : Regions of a Tooth Slide 14.37a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Crown – exposed part
Outer enamel
Dentin
Pulp cavity
Neck
Region in contact with the gum
Connects crown to root Figure 14.10
Slide 54 : Regions of a Tooth Slide 14.37b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Root
Periodontal membrane attached to the bone
Root canal carrying blood vessels and nerves Figure 14.10
Slide 55 : Pancreas Slide 14.38 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Produces a wide spectrum of digestive enzymes that break down all categories of food
Enzymes are secreted into the duodenum
Alkaline fluid introduced with enzymes neutralizes acidic chyme
Endocrine products of pancreas
Insulin
Glucagons
Slide 56 : Liver Slide 14.39 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Largest gland in the body
Located on the right side of the body under the diaphragm
Consists of four lobes suspended from the diaphragm and abdominal wall by the falciform ligament
Connected to the gall bladder via the common hepatic duct
Slide 57 : Bile Slide 14.40 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Produced by cells in the liver
Composition
Bile salts
Bile pigment (mostly bilirubin from the breakdown of hemoglobin)
Cholesterol
Phospholipids
Electrolytes
Slide 58 : Role of the Liver in Metabolism Slide 14.77 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Several roles in digestion
Detoxifies drugs and alcohol
Degrades hormones
Produce cholesterol, blood proteins (albumin and clotting proteins)
Plays a central role in metabolism
Slide 59 : Gall Bladder Slide 14.41 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Sac found in hollow fossa of liver
Stores bile from the liver by way of the cystic duct
Bile is introduced into the duodenum in the presence of fatty food
Gallstones can cause blockages
Slide 60 : Processes of the Digestive System Slide 14.42a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Ingestion – getting food into the mouth
Propulsion – moving foods from one region of the digestive system to another
Slide 61 : Processes of the Digestive System Slide 14.42b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Peristalsis – alternating waves of contraction
Segmentation – moving materials back and forth to aid in mixing Figure 14.12
Slide 62 : Processes of the Digestive System Slide 14.43 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Mechanical digestion
Mixing of food in the mouth by the tongue
Churning of food in the stomach
Segmentation in the small intestine
Slide 63 : Processes of the Digestive System Slide 14.44 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Chemical Digestion
Enzymes break down food molecules into their building blocks
Each major food group uses different enzymes
Carbohydrates are broken to simple sugars
Proteins are broken to amino acids
Fats are broken to fatty acids and alcohols
Slide 64 : Processes of the Digestive System Slide 14.45 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Absorption
End products of digestion are absorbed in the blood or lymph
Food must enter mucosal cells and then into blood or lymph capillaries
Defecation
Elimination of indigestible substances as feces
Slide 65 : Processes of the Digestive System Slide 14.46 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.11
Slide 66 : Control of Digestive Activity Slide 14.47a Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Mostly controlled by reflexes via the parasympathetic division
Chemical and mechanical receptors are located in organ walls that trigger reflexes
Slide 67 : Control of Digestive Activity Slide 14.47b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Stimuli include:
Stretch of the organ
pH of the contents
Presence of breakdown products
Reflexes include:
Activation or inhibition of glandular secretions
Smooth muscle activity
Slide 68 : Nutrition - Take a Class! Slide 14.63 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Nutrient – substance used by the body for growth, maintenance, and repair
Categories of nutrients
Carbohydrates: simple sugars, starches, fiber
Lipids: triglycerides, phospholipids, fatty acids
Proteins: amino acids
Vitamins
Mineral
Water
Slide 69 : Body Energy Balance Slide 14.83 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Energy intake = total energy output (heat + work + energy storage)
Energy intake is liberated during food oxidation
Energy output
Heat is usually about 60%
Storage energy is in the form of fat or glycogen