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Nandini Arunkumar

General Microbiology, Cell Biology, Intro Biology Teacher
ALEXANDRIA, UNITED STATES

Member since: Aug 03, 2009

Last active on: Sep 29, 2009 at 10:40 PM (EST)

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Teaching Preferences

Online Teaching

Face to Face Teaching

Teaches following Subjects/Exams
General Microbiology (Bachelor of Science: Microbiology)
Language of Instruction: English
Cell Biology (Bachelor of Science: Biochemistry)
Language of Instruction: English
Intro Biology (Bachelor of Science: Biochemistry)
Language of Instruction: English
Teaching Experience

Graduate Teaching Assistant

University of Maryland, College Park, United States

Aug 2000 - Mar 2007

General Microbiology, Cell Biology and Physiology, Immunology, Intoduction toBiology

Professional Experience
Consultant - Regulatory, Cell Culture Development
Ampimmune, Inc., Maryland, United States
Dec 2008 - Present
Research Scientist
CytImmune, Inc., Maryland, United States
Apr 2007 - Nov 2008
Education

Ph.D.

University of Maryland College Park, Maryland, United States

Aug 2000 - Mar 2007

Associations & Membership
Women In Bio
Maryland, United States
Dec 2006 - Present
Publications and Research
Polyvalent Antigens Stabilize B Cell Antigen Receptor Surface Signaling Microdomains
Rathna Thyagarajan, Nandini Arunkumar and Wenxia Song

The B cell Ag receptor (BCR) can distinguish subtle differences in Ag structure and trigger differential responses. In this study, we analyzed the effects of Ag valency on the signaling and Ag-targeting functions of the BCR.

The Effects of Antigen Valency and CpG ODN on B Cells
Nandini Arunkumar

B cells express toll-like receptor 9 (TLR9), that recognizes microbial DNA containing unmethylated cytosyl guanosyl (CpG) sequences. To understand the mechanism for TLR9-induced apoptosis, we compared the effects of CpG containing oligodeoxynucleotides (CpG ODN) on mouse primary, splenic B cells and a mouse lymphoma B cell line, CH27. Our data suggests a differential effect of CpG DNA on primary and lymphoma B cells, which occurs due to differences in NF-?B activation.

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